ETHYL IMIDAZO[1,2-A]PYRAZINE-2-CARBOXYLATE
Ethyl imidazo[1,2-a]pyrazine-2-carboxylate
CAS: 77112-52-8
Molecular Formula: C9H9N3O2
ETHYL IMIDAZO[1,2-A]PYRAZINE-2-CARBOXYLATE - Names and Identifiers
ETHYL IMIDAZO[1,2-A]PYRAZINE-2-CARBOXYLATE - Physico-chemical Properties
| Molecular Formula | C9H9N3O2 |
| Molar Mass | 191.19 |
| Density | 1.33±0.1 g/cm3(Predicted) |
| Melting Point | 175-177 °C(Solv: ethanol (64-17-5)) |
| pKa | 0.78±0.30(Predicted) |
| Storage Condition | Sealed in dry,Room Temperature |
| Sensitive | Irritant |
| MDL | MFCD08460079 |
ETHYL IMIDAZO[1,2-A]PYRAZINE-2-CARBOXYLATE - Risk and Safety
| Hazard Class | IRRITANT |
ETHYL IMIDAZO[1,2-A]PYRAZINE-2-CARBOXYLATE - Introduction
Ethyl imidazo[1,2-a]pyrazine-2-carboxylate is an organic compound whose chemical formula is C10H9N3O2. Here are details about the compound:
Nature:
-Appearance: White or yellowish crystalline solid;
-melting point: about 85-88 ℃;
-Boiling point: about 361.8 ℃;
-Solubility: Soluble in ethanol and chloroform, insoluble in water.
Use:
- Ethyl imidazo[1,2-a]pyrazine-2-carboxylate are widely used in organic synthesis reactions, especially as intermediates for the synthesis of various organic compounds;
-The compound is also used in the field of drug research, such as the development of anti-cancer drugs.
Preparation Method:
Ethyl imidazo[1,2-a]pyrazine-2-carboxylate can be prepared by the following steps:
1. reacting 3-formylimidazo [1,2-a]pyrazine (3-formyl imidazo[1,2-a]pyrazine) with ethyl acetate to generate 3-propionate ethyl imidazo[1,2-a]pyrazine (3-propyl ester imidazo[1,2-a]pyrazine);
2. reacting ethyl 3-propionate imidazo[1,2-a]pyrazine with anhydrous hydrochloric acid to generate Ethyl imidazo[1,2-a]pyrazine-2-carboxylate.
Safety Information:
- Ethyl imidazo[1,2-a]pyrazine-2-carboxylate is a chemical and should be used in a laboratory environment and follow the corresponding safe operating procedures;
-Personal protective equipment, such as lab gloves and goggles, must be worn to avoid contact with skin and eyes;
-avoid inhalation of its dust or vapor, need to operate in a well-ventilated place;
-Keep away from fire and high temperature, and avoid contact with oxidants and other substances;
-In case of swallowing or skin contact, rinse immediately with plenty of water and seek medical help.
Please note that this information is for informational purposes only and that laboratory safety practices and chemical safety data sheets are to be followed.
Nature:
-Appearance: White or yellowish crystalline solid;
-melting point: about 85-88 ℃;
-Boiling point: about 361.8 ℃;
-Solubility: Soluble in ethanol and chloroform, insoluble in water.
Use:
- Ethyl imidazo[1,2-a]pyrazine-2-carboxylate are widely used in organic synthesis reactions, especially as intermediates for the synthesis of various organic compounds;
-The compound is also used in the field of drug research, such as the development of anti-cancer drugs.
Preparation Method:
Ethyl imidazo[1,2-a]pyrazine-2-carboxylate can be prepared by the following steps:
1. reacting 3-formylimidazo [1,2-a]pyrazine (3-formyl imidazo[1,2-a]pyrazine) with ethyl acetate to generate 3-propionate ethyl imidazo[1,2-a]pyrazine (3-propyl ester imidazo[1,2-a]pyrazine);
2. reacting ethyl 3-propionate imidazo[1,2-a]pyrazine with anhydrous hydrochloric acid to generate Ethyl imidazo[1,2-a]pyrazine-2-carboxylate.
Safety Information:
- Ethyl imidazo[1,2-a]pyrazine-2-carboxylate is a chemical and should be used in a laboratory environment and follow the corresponding safe operating procedures;
-Personal protective equipment, such as lab gloves and goggles, must be worn to avoid contact with skin and eyes;
-avoid inhalation of its dust or vapor, need to operate in a well-ventilated place;
-Keep away from fire and high temperature, and avoid contact with oxidants and other substances;
-In case of swallowing or skin contact, rinse immediately with plenty of water and seek medical help.
Please note that this information is for informational purposes only and that laboratory safety practices and chemical safety data sheets are to be followed.
Last Update：2024-04-09 15:18:08
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